Characterization of Bipolar Disorder Patient-Specific Induced Pluripotent Stem Cells from a Family Reveals Neurodevelopmental and mRNA Expression Abnormalities

Bipolar disorder (BD) is a common neuropsychiatric disorder characterized by chronic recurrent episodes of depression and mania. Despite evidence for high heritability of BD, little is known about its underlying pathophysiology. To develop new tools for investigating the molecular and cellular basis...

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Detalles Bibliográficos
Autores principales: Madison, Jon M., Zhou, Fen, Nigam, Aparna, Hussain, Ali, Barker, Douglas D., Nehme, Ralda, van der Ven, Karlijn, Hsu, Jenny, Wolf, Pavlina, Fleishman, Morgan, O’Dushlaine, Colm, Rose, Sam, Chambert, Kimberly, Lau, Frank H., Ahfeldt, Tim, Rueckert, Erroll H., Sheridan, Steven D., Fass, Daniel M., Nemesh, James, Mullen, Thomas E., Daheron, Laurence, McCarroll, Steve, Sklar, Pamela, Perlis, Roy H., Haggarty, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4440839/
https://www.ncbi.nlm.nih.gov/pubmed/25733313
http://dx.doi.org/10.1038/mp.2015.7

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