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Bioavailability and biodistribution of differently charged polystyrene nanoparticles upon oral exposure in rats
The likelihood of oral exposure to nanoparticles (NPs) is increasing, and it is necessary to evaluate the oral bioavailability of NPs. In vitro approaches could help reducing animal studies, but validation against in vivo studies is essential. Previously, we assessed the translocation of 50 nm polys...
Autores principales: | Walczak, Agata P., Hendriksen, Peter J. M., Woutersen, Ruud A., van der Zande, Meike, Undas, Anna K., Helsdingen, Richard, van den Berg, Hans H. J., Rietjens, Ivonne M. C. M., Bouwmeester, Hans |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4440892/ https://www.ncbi.nlm.nih.gov/pubmed/26028989 http://dx.doi.org/10.1007/s11051-015-3029-y |
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