Cargando…

Curcuminoids and ω-3 fatty acids with anti-oxidants potentiate cytotoxicity of natural killer cells against pancreatic ductal adenocarcinoma cells and inhibit interferon γ production

Pancreatic cancer has a poor prognosis attributed in part to immune suppression and deactivation of natural killer (NK) cells. Curcuminoids have a potential for improving the therapy of pancreatic cancer given promising results in cancer models and a clinical trial, but their oral absorption is limi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Halder, Ramesh C., Almasi, Anasheh, Sagong, Bien, Leung, Jessica, Jewett, Anahid, Fiala, Milan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2015
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4440907/ https://www.ncbi.nlm.nih.gov/pubmed/26052286 http://dx.doi.org/10.3389/fphys.2015.00129

Ejemplares similares

Tumor Induced Inactivation of Natural Killer Cell Cytotoxic Function; Implication in Growth, Expansion and Differentiation of Cancer Stem Cells
por: Jewett, Anahid, et al.
Publicado: (2011)

Immunotherapy of Mild Cognitive Impairment by ω-3 Supplementation: Why Are Amyloid-β Antibodies and ω-3 Not Working in Clinical Trials?
por: Fiala, Milan, et al.
Publicado: (2018)

Cystatin F Affects Natural Killer Cell Cytotoxicity
por: Perišić Nanut, Milica, et al.
Publicado: (2017)

Dual Functions of Natural Killer Cells in Selection and Differentiation of Stem Cells; Role in Regulation of Inflammation and Regeneration of Tissues
por: Jewett, Anahid, et al.
Publicado: (2012)

Split anergized natural killer cells halt inflammation by inducing stem cell differentiation, resistance to NK cell cytotoxicity and prevention of cytokine and chemokine secretion
por: Tseng, Han-Ching, et al.
Publicado: (2015)

Curcumin and Omega-3 Fatty Acids Enhance NK Cell-Induced Apoptosis of Pancreatic Cancer Cells but Curcumin Inhibits Interferon-γ Production: Benefits of Omega-3 with Curcumin against Cancer
por: Fiala, Milan
Publicado: (2015)

Role of Uterine Natural Killer Cells and Interferon γ in Placental Development
por: Redline, Raymond W.
Publicado: (2000)

Regulation of split anergy in natural killer cells by inhibition of cathepsins C and H and cystatin F
por: Magister, Špela, et al.
Publicado: (2015)

Induction of Split Anergy Conditions Natural Killer Cells to Promote Differentiation of Stem Cells through Cell–Cell Contact and Secreted Factors
por: Tseng, Han-Ching, et al.
Publicado: (2014)

Reinforced Cytotoxicity of Lymphokine‐activated Killer Cells toward Glioma Cells by Transfection of the Killer Cells with the γ‐Interferon Gene
por: Mizuno, Masaaki, et al.
Publicado: (1995)

Increased intermediate M1-M2 macrophage polarization and improved cognition in mild cognitive impairment patients on ω-3 supplementation
por: Famenini, Sam, et al.
Publicado: (2017)

Interferon-γ-Mediated Natural Killer Cell Activation by an Aqueous Panax ginseng Extract
por: Takeda, Kazuyoshi, et al.
Publicado: (2015)

Increased level and interferon-γ production of circulating natural killer cells in patients with scrub typhus
por: Kang, Seung-Ji, et al.
Publicado: (2017)

The Potential Effect of Novel Coronavirus SARS-CoV-2 on NK Cells; A Perspective on Potential Therapeutic Interventions
por: Jewett, Anahid
Publicado: (2020)

Augmentation of IFN-γ by bone marrow derived immune cells in the presence of severe suppression of IFN-γ in gingivae induced by zoledronic acid and denosumab in Hu-BLT mice model of ONJ
por: Kaur, Kawaljit, et al.
Publicado: (2023)

Cross-Talk with Myeloid Accessory Cells Regulates Human Natural Killer Cell Interferon-γ Responses to Malaria
por: Newman, Kirsty C, et al.
Publicado: (2006)

Deficiencies in Natural Killer Cell Numbers, Expansion, and Function at the Pre-Neoplastic Stage of Pancreatic Cancer by KRAS Mutation in the Pancreas of Obese Mice
por: Kaur, Kawaljit, et al.
Publicado: (2018)

GAA•TTC repeat expansion in human cells is mediated by mismatch repair complex MutLγ and depends upon the endonuclease domain in MLH3 isoform one
por: Halabi, Anasheh, et al.
Publicado: (2018)

Natural Killer Cells Are Characterized by the Concomitantly Increased Interferon-γ and Cytotoxicity in Acute Resolved Hepatitis B Patients
por: Zhao, Juanjuan, et al.
Publicado: (2012)

Recent advances in the investigation of curcuminoids
por: Itokawa, Hideji, et al.
Publicado: (2008)

In vitro Effect of Recombinant Feline Interferon-Ω (rFeIFN-Ω) on the Primary CanineTransmissible Venereal Tumor Culture
por: Setthawongsin, Chanokchon, et al.
Publicado: (2019)

Synthesis of curcuminoid-imprinted polymers applied to the solid-phase extraction of curcuminoids from turmeric samples
por: Thongchai, Wisanu, et al.
Publicado: (2018)

Natural Killer Cells: Diverse Functions in Tumor Immunity and Defects in Pre-neoplastic and Neoplastic Stages of Tumorigenesis
por: Jewett, Anahid, et al.
Publicado: (2019)

Increasing Affinity of Interferon-γ Receptor 1 to Interferon-γ by Computer-Aided Design
por: Mikulecký, Pavel, et al.
Publicado: (2013)

Reversed-phase High-performance Liquid Chromatography Method for Analysis of Curcuminoids and Curcuminoid-loaded Liposome Formulation
por: Jangle, R. D., et al.
Publicado: (2013)

Efficacy of Oral Curcuminoid Fraction from Curcuma xanthorrhiza and Curcuminoid Cider in High-cholesterol Fed Rats
por: Mauren, Flavia Maria, et al.
Publicado: (2016)

Impairment of Natural Killer Cytotoxic Activity and Interferon γ Production in Ccaat/Enhancer Binding Protein γ–Deficient Mice
por: Kaisho, Tsuneyasu, et al.
Publicado: (1999)

Thymoglobulin, interferon-γ and interleukin-2 efficiently expand cytokine-induced killer (CIK) cells in clinical-grade cultures
por: Bonanno, Giuseppina, et al.
Publicado: (2010)

25KDa branched polyethylenimine increases interferon-γ production in natural killer cells via improving translation efficiency
por: Ko, Eun-Su, et al.
Publicado: (2023)

Differential Cytotoxicity but Augmented IFN-γ Secretion by NK Cells after Interaction with Monocytes from Humans, and Those from Wild Type and Myeloid-Specific COX-2 Knockout Mice
por: Tseng, Han-Ching, et al.
Publicado: (2015)

Human Umbilical Cord-Derived Mesenchymal Stem Cells Utilize Activin-A to Suppress Interferon-γ Production by Natural Killer Cells
por: Chatterjee, Debanjana, et al.
Publicado: (2014)

Natural killer cells and innate lymphoid cells 1 tune anxiety-like behavior and memory in mice via interferon-γ and acetylcholine
por: Garofalo, Stefano, et al.
Publicado: (2023)

Mode of regulation of natural killer cell activity by interferon
por: Minato, N, et al.
Publicado: (1980)

Increased Lysis of Stem Cells but Not Their Differentiated Cells by Natural Killer Cells; De-Differentiation or Reprogramming Activates NK Cells
por: Tseng, Han-Ching, et al.
Publicado: (2010)

Dose escalation of a curcuminoid formulation
por: Lao, Christopher D, et al.
Publicado: (2006)

The antioxidant activity of some curcuminoids and chalcones
por: Sökmen, Münevver, et al.
Publicado: (2016)

Infiltrating natural killer cells bind, lyse and increase chemotherapy efficacy in glioblastoma stem-like tumorospheres
por: Breznik, Barbara, et al.
Publicado: (2022)

Special Issue on Immune Responses in Tumors and Non-Transformed Inflammatory Microenvironments
por: Jewett, Anahid
Publicado: (2012)

Treatment with Recombinant Interleukin-15 (IL-15) Increases the Number of T Cells and Natural Killer (NK) Cells and Levels of Interferon-γ (IFN-γ) in a Rat Model of Sepsis
por: Zhao, Xianyuan, et al.
Publicado: (2019)

Malignant germ cell tumours of the testis express interferon-γ, but are resistant to endogenous interferon-γ
por: Schweyer, S, et al.
Publicado: (2003)

Cannot write session to /tmp/vufind_sessions/sess_39fvcouvj556sbjmgk46khbm02