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Proposal of an Appropriate Decalcification Method of Bone Marrow Biopsy Specimens in the Era of Expanding Genetic Molecular Study

BACKGROUND: The conventional method for decalcification of bone specimens uses hydrochloric acid (HCl) and is notorious for damaging cellular RNA, DNA, and proteins, thus complicating molecular and immunohistochemical analyses. A method that can effectively decalcify while preserving genetic materia...

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Detalles Bibliográficos
Autores principales: Choi, Sung-Eun, Hong, Soon Won, Yoon, Sun Och
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Pathologists and the Korean Society for Cytopathology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4440935/
https://www.ncbi.nlm.nih.gov/pubmed/26018515
http://dx.doi.org/10.4132/jptm.2015.03.16

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