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IDH Mutation Analysis in Ewing Sarcoma Family Tumors
BACKGROUND: Isocitrate dehydrogenase (IDH) catalyzes the oxidative decarboxylation of isocitrate to yield α-ketoglutarate (α-KG) with production of reduced nicotinamide adenine dinucleotide (NADH). Dysfunctional IDH leads to reduced production of α-KG and NADH and increased production of 2-hydroxygl...
Autores principales: | Na, Ki Yong, Noh, Byeong-Joo, Sung, Ji-Youn, Kim, Youn Wha, Santini Araujo, Eduardo, Park, Yong-Koo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Society of Pathologists and the Korean Society for Cytopathology
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4440938/ https://www.ncbi.nlm.nih.gov/pubmed/26018518 http://dx.doi.org/10.4132/jptm.2015.04.14 |
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