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Widespread disruption of host transcription termination in HSV-1 infection
Herpes simplex virus 1 (HSV-1) is an important human pathogen and a paradigm for virus-induced host shut-off. Here we show that global changes in transcription and RNA processing and their impact on translation can be analysed in a single experimental setting by applying 4sU-tagging of newly transcr...
Autores principales: | Rutkowski, Andrzej J., Erhard, Florian, L'Hernault, Anne, Bonfert, Thomas, Schilhabel, Markus, Crump, Colin, Rosenstiel, Philip, Efstathiou, Stacey, Zimmer, Ralf, Friedel, Caroline C., Dölken, Lars |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4441252/ https://www.ncbi.nlm.nih.gov/pubmed/25989971 http://dx.doi.org/10.1038/ncomms8126 |
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