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Effect of treatment delay, age, and stroke severity on the effects of intravenous thrombolysis with alteplase for acute ischaemic stroke: a meta-analysis of individual patient data from randomised trials

BACKGROUND: Alteplase is effective for treatment of acute ischaemic stroke but debate continues about its use after longer times since stroke onset, in older patients, and among patients who have had the least or most severe strokes. We assessed the role of these factors in affecting good stroke out...

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Detalles Bibliográficos
Autores principales: Emberson, Jonathan, Lees, Kennedy R, Lyden, Patrick, Blackwell, Lisa, Albers, Gregory, Bluhmki, Erich, Brott, Thomas, Cohen, Geoff, Davis, Stephen, Donnan, Geoffrey, Grotta, James, Howard, George, Kaste, Markku, Koga, Masatoshi, von Kummer, Ruediger, Lansberg, Maarten, Lindley, Richard I, Murray, Gordon, Olivot, Jean Marc, Parsons, Mark, Tilley, Barbara, Toni, Danilo, Toyoda, Kazunori, Wahlgren, Nils, Wardlaw, Joanna, Whiteley, William, del Zoppo, Gregory J, Baigent, Colin, Sandercock, Peter, Hacke, Werner
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4441266/
https://www.ncbi.nlm.nih.gov/pubmed/25106063
http://dx.doi.org/10.1016/S0140-6736(14)60584-5

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