A diversity-oriented synthesis strategy enabling the combinatorial-type variation of macrocyclic peptidomimetic scaffolds

Macrocyclic peptidomimetics are associated with a broad range of biological activities. However, despite such potentially valuable properties, the macrocyclic peptidomimetic structural class is generally considered as being poorly explored within drug discovery. This has been attributed to the lack...

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Detalles Bibliográficos
Autores principales: Isidro-Llobet, Albert, Hadje Georgiou, Kathy, Galloway, Warren R. J. D., Giacomini, Elisa, Hansen, Mette R., Méndez-Abt, Gabriela, Tan, Yaw Sing, Carro, Laura, Sore, Hannah F., Spring, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2015
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4441267/
https://www.ncbi.nlm.nih.gov/pubmed/25778821
http://dx.doi.org/10.1039/c5ob00371g

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