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The novel desmopressin analogue [V(4)Q(5)]dDAVP inhibits angiogenesis, tumour growth and metastases in vasopressin type 2 receptor-expressing breast cancer models
Desmopressin (dDAVP) is a safe haemostatic agent with previously reported antitumour activity. It acts as a selective agonist for the V2 vasopressin membrane receptor (V2r) present on tumour cells and microvasculature. The purpose of this study was to evaluate the novel peptide derivative [V(4)Q(5)]...
Autores principales: | GARONA, JUAN, PIFANO, MARINA, ORLANDO, ULISES D., PASTRIAN, MARIA B., IANNUCCI, NANCY B., ORTEGA, HUGO H., PODESTA, ERNESTO J., GOMEZ, DANIEL E., RIPOLL, GISELLE V., ALONSO, DANIEL F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4441290/ https://www.ncbi.nlm.nih.gov/pubmed/25846632 http://dx.doi.org/10.3892/ijo.2015.2952 |
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