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Annexin A1 Preferentially Predicts Poor Prognosis of Basal-Like Breast Cancer Patients by Activating mTOR-S6 Signaling

INTRODUCTION: Annexin A1 (ANXA1) is an anti-inflammatory protein reported to play a role in cell proliferation and apoptosis, and to be deregulated in breast cancer. The exact role of annexin A1 in the biology of breast cancer remains unclear. We hypothesized that the annexin A1 plays an oncogenic r...

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Detalles Bibliográficos
Autores principales: Bhardwaj, Anjana, Ganesan, Nivetha, Tachibana, Kazunoshin, Rajapakshe, Kimal, Albarracin, Constance T., Gunaratne, Preethi H., Coarfa, Cristian, Bedrosian, Isabelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4441370/
https://www.ncbi.nlm.nih.gov/pubmed/26000884
http://dx.doi.org/10.1371/journal.pone.0127678