Ribonucleotide Reductase Subunit M2 Predicts Survival in Subgroups of Patients with Non-Small Cell Lung Carcinoma: Effects of Gender and Smoking Status

BACKGROUND: Ribonucleotide reductase catalyzes the conversion of ribonucleotide diphosphates to deoxyribonucleotide diphosphates. The functional enzyme consists of two subunits - one large (RRM1) and one small (RRM2 or RRM2b) subunit. Expression levels of each subunit have been implicated in prognos...

Descripción completa

Detalles Bibliográficos
Autores principales: Mah, Vei, Alavi, Mohammad, Márquez-Garbán, Diana C., Maresh, Erin L., Kim, Sara R., Horvath, Steve, Bagryanova, Lora, Huerta-Yepez, Sara, Chia, David, Pietras, Richard, Goodglick, Lee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4441434/
https://www.ncbi.nlm.nih.gov/pubmed/26001082
http://dx.doi.org/10.1371/journal.pone.0127600

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4441434/
https://www.ncbi.nlm.nih.gov/pubmed/26001082
http://dx.doi.org/10.1371/journal.pone.0127600

Ejemplares similares