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Metabolic Needs and Capabilities of Toxoplasma gondii through Combined Computational and Experimental Analysis

Toxoplasma gondii is a human pathogen prevalent worldwide that poses a challenging and unmet need for novel treatment of toxoplasmosis. Using a semi-automated reconstruction algorithm, we reconstructed a genome-scale metabolic model, ToxoNet1. The reconstruction process and flux-balance analysis of...

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Detalles Bibliográficos
Autores principales:	Tymoshenko, Stepan, Oppenheim, Rebecca D., Agren, Rasmus, Nielsen, Jens, Soldati-Favre, Dominique, Hatzimanikatis, Vassily
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4441489/ https://www.ncbi.nlm.nih.gov/pubmed/26001086 http://dx.doi.org/10.1371/journal.pcbi.1004261

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