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The Amount of Keratins Matters for Stress Protection of the Colonic Epithelium

Keratins (K) are important for epithelial stress protection as evidenced by keratin mutations predisposing to human liver diseases and possibly inflammatory bowel diseases. A role for K8 in the colon is supported by the ulcerative colitis-phenotype with epithelial hyperproliferation and abnormal ion...

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Detalles Bibliográficos
Autores principales: Asghar, M. Nadeem, Silvander, Jonas S. G., Helenius, Terhi O., Lähdeniemi, Iris A. K., Alam, Catharina, Fortelius, Lina E., Holmsten, Rickard O., Toivola, Diana M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4441500/
https://www.ncbi.nlm.nih.gov/pubmed/26000979
http://dx.doi.org/10.1371/journal.pone.0127436

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