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The Roles of ROS and Caspases in TRAIL-Induced Apoptosis and Necroptosis in Human Pancreatic Cancer Cells
Death signaling provided by tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) can induce death in cancer cells with little cytotoxicity to normal cells; this cell death has been thought to involve caspase-dependent apoptosis. Reactive oxygen species (ROS) are also mediators that...
Autores principales: | Zhang, Min, Harashima, Nanae, Moritani, Tamami, Huang, Weidong, Harada, Mamoru |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4441514/ https://www.ncbi.nlm.nih.gov/pubmed/26000607 http://dx.doi.org/10.1371/journal.pone.0127386 |
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