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The Roles of ROS and Caspases in TRAIL-Induced Apoptosis and Necroptosis in Human Pancreatic Cancer Cells

Death signaling provided by tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) can induce death in cancer cells with little cytotoxicity to normal cells; this cell death has been thought to involve caspase-dependent apoptosis. Reactive oxygen species (ROS) are also mediators that...

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Detalles Bibliográficos
Autores principales: Zhang, Min, Harashima, Nanae, Moritani, Tamami, Huang, Weidong, Harada, Mamoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4441514/
https://www.ncbi.nlm.nih.gov/pubmed/26000607
http://dx.doi.org/10.1371/journal.pone.0127386

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