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To translate, or not to translate: viral and host mRNA regulation by interferon-stimulated genes
Type I interferon (IFN) is one of the first lines of cellular defense against viral pathogens. As a result of IFN signaling, a wide array of IFN-stimulated gene (ISG) products is upregulated to target different stages of the viral life cycle. We review recent findings implicating a subset of ISGs in...
Autores principales: | Li, Melody M.H., MacDonald, Margaret R., Rice, Charles M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Ltd.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4441850/ https://www.ncbi.nlm.nih.gov/pubmed/25748385 http://dx.doi.org/10.1016/j.tcb.2015.02.001 |
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