Localized Relapse of Primary Plasma Cell Leukaemia in the Central Nervous System

Primary plasma cell leukaemia (pPCL) is a rare and aggressive form of plasma cell malignancies with a very poor prognosis. Compared to other plasma cell malignancies the tendency to extramedullary spread is increased; however central nervous system (CNS) involvement is rare and only reported in few...

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Detalles Bibliográficos
Autores principales: Eskelund, Christian W., Andersen, Niels Frost
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4441999/
https://www.ncbi.nlm.nih.gov/pubmed/26064713
http://dx.doi.org/10.1155/2015/273565
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author Eskelund, Christian W.
Andersen, Niels Frost
author_facet Eskelund, Christian W.
Andersen, Niels Frost
author_sort Eskelund, Christian W.
collection PubMed
description Primary plasma cell leukaemia (pPCL) is a rare and aggressive form of plasma cell malignancies with a very poor prognosis. Compared to other plasma cell malignancies the tendency to extramedullary spread is increased; however central nervous system (CNS) involvement is rare and only reported in few cases. We report the case of a 61-year-old man who was diagnosed with pPCL and achieved a complete remission after autologous stem cell transplantation but had a relapse in the CNS without systemic disease.
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spelling pubmed-44419992015-06-10 Localized Relapse of Primary Plasma Cell Leukaemia in the Central Nervous System Eskelund, Christian W. Andersen, Niels Frost Case Rep Hematol Case Report Primary plasma cell leukaemia (pPCL) is a rare and aggressive form of plasma cell malignancies with a very poor prognosis. Compared to other plasma cell malignancies the tendency to extramedullary spread is increased; however central nervous system (CNS) involvement is rare and only reported in few cases. We report the case of a 61-year-old man who was diagnosed with pPCL and achieved a complete remission after autologous stem cell transplantation but had a relapse in the CNS without systemic disease. Hindawi Publishing Corporation 2015 2015-05-10 /pmc/articles/PMC4441999/ /pubmed/26064713 http://dx.doi.org/10.1155/2015/273565 Text en Copyright © 2015 C. W. Eskelund and N. F. Andersen. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Eskelund, Christian W.
Andersen, Niels Frost
Localized Relapse of Primary Plasma Cell Leukaemia in the Central Nervous System
title Localized Relapse of Primary Plasma Cell Leukaemia in the Central Nervous System
title_full Localized Relapse of Primary Plasma Cell Leukaemia in the Central Nervous System
title_fullStr Localized Relapse of Primary Plasma Cell Leukaemia in the Central Nervous System
title_full_unstemmed Localized Relapse of Primary Plasma Cell Leukaemia in the Central Nervous System
title_short Localized Relapse of Primary Plasma Cell Leukaemia in the Central Nervous System
title_sort localized relapse of primary plasma cell leukaemia in the central nervous system
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4441999/
https://www.ncbi.nlm.nih.gov/pubmed/26064713
http://dx.doi.org/10.1155/2015/273565
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