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SMC condensin entraps chromosomal DNA by an ATP hydrolysis dependent loading mechanism in Bacillus subtilis

Smc–ScpAB forms elongated, annular structures that promote chromosome segregation, presumably by compacting and resolving sister DNA molecules. The mechanistic basis for its action, however, is only poorly understood. Here, we have established a physical assay to determine whether the binding of con...

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Detalles Bibliográficos
Autores principales: Wilhelm, Larissa, Bürmann, Frank, Minnen, Anita, Shin, Ho-Chul, Toseland, Christopher P, Oh, Byung-Ha, Gruber, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4442127/
https://www.ncbi.nlm.nih.gov/pubmed/25951515
http://dx.doi.org/10.7554/eLife.06659

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