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SMC condensin entraps chromosomal DNA by an ATP hydrolysis dependent loading mechanism in Bacillus subtilis
Smc–ScpAB forms elongated, annular structures that promote chromosome segregation, presumably by compacting and resolving sister DNA molecules. The mechanistic basis for its action, however, is only poorly understood. Here, we have established a physical assay to determine whether the binding of con...
Autores principales: | Wilhelm, Larissa, Bürmann, Frank, Minnen, Anita, Shin, Ho-Chul, Toseland, Christopher P, Oh, Byung-Ha, Gruber, Stephan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4442127/ https://www.ncbi.nlm.nih.gov/pubmed/25951515 http://dx.doi.org/10.7554/eLife.06659 |
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