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Crystal structure of human nicotinic acid phosphoribosyltransferase

Nicotinic acid phosphoribosyltransferase (EC 2.4.2.11) (NaPRTase) is the rate-limiting enzyme in the three-step Preiss–Handler pathway for the biosynthesis of NAD. The enzyme catalyzes the conversion of nicotinic acid (Na) and 5-phosphoribosyl-1-pyrophosphate (PRPP) to nicotinic acid mononucleotide...

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Detalles Bibliográficos
Autores principales:	Marletta, Ada Serena, Massarotti, Alberto, Orsomando, Giuseppe, Magni, Giulio, Rizzi, Menico, Garavaglia, Silvia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4442680/ https://www.ncbi.nlm.nih.gov/pubmed/26042198 http://dx.doi.org/10.1016/j.fob.2015.05.002

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