First data on Pneumocystis jirovecii colonization in patients with respiratory diseases in North Lebanon

Pneumocystis colonization may play a role in transmission and local inflammatory response. It was explored in patients with respiratory diseases in North Lebanon. Overall prevalence reached only 5.2% (95% CI 2.13–10.47) but it was higher (17.3%) in the subpopulation of patients with chronic obstruct...

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Autores principales: Khalife, S., Aliouat, E.M., Aliouat-Denis, C.M., Gantois, N., Devos, P., Mallat, H., Dei-Cas, E., Dabboussi, F., Hamze, M., Fréalle, E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
New Microbes in Humans
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4442690/
https://www.ncbi.nlm.nih.gov/pubmed/26042187
http://dx.doi.org/10.1016/j.nmni.2015.02.006
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author Khalife, S.
Aliouat, E.M.
Aliouat-Denis, C.M.
Gantois, N.
Devos, P.
Mallat, H.
Dei-Cas, E.
Dabboussi, F.
Hamze, M.
Fréalle, E.
author_facet Khalife, S.
Aliouat, E.M.
Aliouat-Denis, C.M.
Gantois, N.
Devos, P.
Mallat, H.
Dei-Cas, E.
Dabboussi, F.
Hamze, M.
Fréalle, E.
author_sort Khalife, S.
collection PubMed
description Pneumocystis colonization may play a role in transmission and local inflammatory response. It was explored in patients with respiratory diseases in North Lebanon. Overall prevalence reached only 5.2% (95% CI 2.13–10.47) but it was higher (17.3%) in the subpopulation of patients with chronic obstructive pulmonary disease (COPD). COPD was the only factor associated with a significantly increased risk of colonization. mtLSU genotyping revealed predominance of genotype 2, identified in five patients (71.4%), including one patient who had co-infection with genotype 3. These first data in North Lebanon confirm Pneumocystis circulation among patients with respiratory diseases and the potential for transmission to immunocompromised patients.
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spelling pubmed-44426902015-06-03 First data on Pneumocystis jirovecii colonization in patients with respiratory diseases in North Lebanon Khalife, S. Aliouat, E.M. Aliouat-Denis, C.M. Gantois, N. Devos, P. Mallat, H. Dei-Cas, E. Dabboussi, F. Hamze, M. Fréalle, E. New Microbes New Infect New Microbes in Humans Pneumocystis colonization may play a role in transmission and local inflammatory response. It was explored in patients with respiratory diseases in North Lebanon. Overall prevalence reached only 5.2% (95% CI 2.13–10.47) but it was higher (17.3%) in the subpopulation of patients with chronic obstructive pulmonary disease (COPD). COPD was the only factor associated with a significantly increased risk of colonization. mtLSU genotyping revealed predominance of genotype 2, identified in five patients (71.4%), including one patient who had co-infection with genotype 3. These first data in North Lebanon confirm Pneumocystis circulation among patients with respiratory diseases and the potential for transmission to immunocompromised patients. Elsevier 2015-03-04 /pmc/articles/PMC4442690/ /pubmed/26042187 http://dx.doi.org/10.1016/j.nmni.2015.02.006 Text en © 2015 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle New Microbes in Humans
Khalife, S.
Aliouat, E.M.
Aliouat-Denis, C.M.
Gantois, N.
Devos, P.
Mallat, H.
Dei-Cas, E.
Dabboussi, F.
Hamze, M.
Fréalle, E.
First data on Pneumocystis jirovecii colonization in patients with respiratory diseases in North Lebanon
title First data on Pneumocystis jirovecii colonization in patients with respiratory diseases in North Lebanon
title_full First data on Pneumocystis jirovecii colonization in patients with respiratory diseases in North Lebanon
title_fullStr First data on Pneumocystis jirovecii colonization in patients with respiratory diseases in North Lebanon
title_full_unstemmed First data on Pneumocystis jirovecii colonization in patients with respiratory diseases in North Lebanon
title_short First data on Pneumocystis jirovecii colonization in patients with respiratory diseases in North Lebanon
title_sort first data on pneumocystis jirovecii colonization in patients with respiratory diseases in north lebanon
topic New Microbes in Humans
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4442690/
https://www.ncbi.nlm.nih.gov/pubmed/26042187
http://dx.doi.org/10.1016/j.nmni.2015.02.006
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