Cargando…

Receptor dimerization dynamics as a regulatory valve for plasticity of type I interferon signaling

Type I interferons (IFNs) activate differential cellular responses through a shared cell surface receptor composed of the two subunits, IFNAR1 and IFNAR2. We propose here a mechanistic model for how IFN receptor plasticity is regulated on the level of receptor dimerization. Quantitative single-molec...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wilmes, Stephan, Beutel, Oliver, Li, Zhi, Francois-Newton, Véronique, Richter, Christian P., Janning, Dennis, Kroll, Cindy, Hanhart, Patrizia, Hötte, Katharina, You, Changjiang, Uzé, Gilles, Pellegrini, Sandra, Piehler, Jacob
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2015
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4442803/ https://www.ncbi.nlm.nih.gov/pubmed/26008745 http://dx.doi.org/10.1083/jcb.201412049

Ejemplares similares

USP18-Based Negative Feedback Control Is Induced by Type I and Type III Interferons and Specifically Inactivates Interferon α Response
por: François-Newton, Véronique, et al.
Publicado: (2011)

Receptor dimer stabilization by hierarchical plasma membrane microcompartments regulates cytokine signaling
por: You, Changjiang, et al.
Publicado: (2016)

Differential Activity of Type I Interferon Subtypes for Dendritic Cell Differentiation
por: Garcin, Geneviève, et al.
Publicado: (2013)

Assessment of mTOR-Dependent Translational Regulation of Interferon Stimulated Genes
por: Livingstone, Mark, et al.
Publicado: (2015)

Ligand-induced type II interleukin-4 receptor dimers are sustained by rapid re-association within plasma membrane microcompartments
por: Richter, David, et al.
Publicado: (2017)

Live cell micropatterning reveals the dynamics of signaling complexes at the plasma membrane
por: Löchte, Sara, et al.
Publicado: (2014)

Dumbbell gold nanoparticle dimer antennas with advanced optical properties
por: Herrmann, Janning F, et al.
Publicado: (2018)

Single molecule super-resolution imaging of proteins in living Salmonella enterica using self-labelling enzymes
por: Barlag, Britta, et al.
Publicado: (2016)

Dendrites help mitigate the plasticity-stability dilemma
por: Wilmes, Katharina A., et al.
Publicado: (2023)

Interferons at age 50: past, current and future impact on biomedicine
por: Borden, Ernest C., et al.
Publicado: (2007)

Single-molecule tracking of tau reveals fast kiss-and-hop interaction with microtubules in living neurons
por: Janning, Dennis, et al.
Publicado: (2014)

Inhibitory microcircuits for top-down plasticity of sensory representations
por: Wilmes, Katharina Anna, et al.
Publicado: (2019)

STAT2 is an essential adaptor in USP18-mediated suppression of type I interferon signaling
por: Arimoto, Kei-ichiro, et al.
Publicado: (2017)

Four-color single-molecule imaging with engineered tags resolves the molecular architecture of signaling complexes in the plasma membrane
por: Sotolongo Bellón, Junel, et al.
Publicado: (2022)

Inhibition as a Binary Switch for Excitatory Plasticity in Pyramidal Neurons
por: Wilmes, Katharina A., et al.
Publicado: (2016)

Binding of interferon reduces the force of unfolding for interferon receptor 1
por: Chuartzman, Silvia G., et al.
Publicado: (2017)

Spatiotemporal control of interferon-induced JAK/STAT signalling and gene transcription by the retromer complex
por: Chmiest, Daniela, et al.
Publicado: (2016)

Cholesterol-dependent Conformational Plasticity in GPCR Dimers
por: Prasanna, Xavier, et al.
Publicado: (2016)

Self-assembly of robust gold nanoparticle monolayer architectures for quantitative protein interaction analysis by LSPR spectroscopy
por: Flesch, Julia, et al.
Publicado: (2020)

Close-packed silane nanodot arrays by capillary nanostamping coupled with heterocyclic silane ring opening
por: Philippi, Michael, et al.
Publicado: (2019)

Comprehensive characterization of ligand‐induced plasticity changes in a dimeric enzyme
por: Baettig, Oliver M., et al.
Publicado: (2016)

Harnessing Mechanistic Knowledge on Beneficial Versus Deleterious IFN-I Effects to Design Innovative Immunotherapies Targeting Cytokine Activity to Specific Cell Types
por: Tomasello, Elena, et al.
Publicado: (2014)

Shearing of the CENP-A dimerization interface mediates plasticity in the octameric centromeric nucleosome
por: Winogradoff, David, et al.
Publicado: (2015)

Relevance of Ebola virus VP35 homo-dimerization on the type I interferon cascade inhibition
por: Di Palma, Francesco, et al.
Publicado: (2019)

Diagnostic Value of D-Dimer and INR in Patients Suspected to Have Prosthetic Valve Dysfunction
por: Moghadam, Reza Heidari, et al.
Publicado: (2022)

Cyclase-associated protein 2 dimerization regulates cofilin in synaptic plasticity and Alzheimer's disease
por: Pelucchi, Silvia, et al.
Publicado: (2020)

A bispecific Clec9A-PD-L1 targeted type I interferon profoundly reshapes the tumor microenvironment towards an antitumor state
por: Van Lint, Sandra, et al.
Publicado: (2023)

Determinants of Ligand Specificity and Functional Plasticity in Type I Interferon Signaling
por: Kirby, Duncan, et al.
Publicado: (2021)

H2A-H2B Histone Dimer Plasticity and Its Functional Implications
por: Kniazeva, Anastasiia S., et al.
Publicado: (2022)

Assessment of levels of D-dimer and interferon-γ in pediatric patients with Mycoplasma pneumoniae pneumonia and its clinical implication
por: Jin, Xiaoqiu, et al.
Publicado: (2018)

Interferon-armed RBD dimer enhances the immunogenicity of RBD for sterilizing immunity against SARS-CoV-2
por: Sun, Shiyu, et al.
Publicado: (2021)

Cell diversity and plasticity during atrioventricular heart valve EMTs
por: Lotto, Jeremy, et al.
Publicado: (2023)

Enhanced anti-HCV activity of interferon alpha 17 subtype
por: Dubois, Aurelie, et al.
Publicado: (2009)

Nanoscopic anatomy of dynamic multi-protein complexes at membranes resolved by graphene-induced energy transfer
por: Füllbrunn, Nadia, et al.
Publicado: (2021)

Constraints On High Energy Phenomena From Low Energy<br> Nuclear Physics
por: Hanhart, C
Publicado: (2001)

Aortic valve bypass for high‐risk patients with symptomatic aortic stenosis: A case report
por: Ye, Yanqiong, et al.
Publicado: (2021)

Synergistic inhibition of human cytomegalovirus replication by interferon-alpha/beta and interferon-gamma
por: Sainz, Bruno, et al.
Publicado: (2005)

A rapid conformational rearrangement of STAT1 dimers is required for termination rather than for amplification of interferon-γ signaling
por: Staab, Julia, et al.
Publicado: (2013)

Structure of angiogenin dimer bound to double-stranded RNA
por: Sievers, Katharina, et al.
Publicado: (2022)

A case of plastic bronchitis after mitral valve surgery in an adult
por: Ogiwara, Masanori, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_sfncb0r8qv2hq0sg1cccmegcf3