Cargando…

BLOC-2 targets recycling endosomal tubules to melanosomes for cargo delivery

Hermansky–Pudlak syndrome (HPS) is a group of disorders characterized by the malformation of lysosome-related organelles, such as pigment cell melanosomes. Three of nine characterized HPS subtypes result from mutations in subunits of BLOC-2, a protein complex with no known molecular function. In thi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dennis, Megan K., Mantegazza, Adriana R., Snir, Olivia L., Tenza, Danièle, Acosta-Ruiz, Amanda, Delevoye, Cédric, Zorger, Richard, Sitaram, Anand, de Jesus-Rojas, Wilfredo, Ravichandran, Keerthana, Rux, John, Sviderskaya, Elena V., Bennett, Dorothy C., Raposo, Graça, Marks, Michael S., Setty, Subba Rao Gangi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2015
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4442807/ https://www.ncbi.nlm.nih.gov/pubmed/26008744 http://dx.doi.org/10.1083/jcb.201410026

Ejemplares similares

Differential recognition of a dileucine-based sorting signal by AP-1 and AP-3 reveals a requirement for both BLOC-1 and AP-3 in delivery of OCA2 to melanosomes
por: Sitaram, Anand, et al.
Publicado: (2012)

Rab9A is required for delivery of cargo from recycling endosomes to melanosomes
por: Mahanty, Sarmistha, et al.
Publicado: (2016)

STX13 regulates cargo delivery from recycling endosomes during melanosome biogenesis
por: Jani, Riddhi Atul, et al.
Publicado: (2015)

BLOC-1 and BLOC-3 regulate VAMP7 cycling to and from melanosomes via distinct tubular transport carriers
por: Dennis, Megan K., et al.
Publicado: (2016)

Rab22A recruits BLOC‐1 and BLOC‐2 to promote the biogenesis of recycling endosomes
por: Shakya, Saurabh, et al.
Publicado: (2018)

Type II phosphatidylinositol 4-kinases function sequentially in cargo delivery from early endosomes to melanosomes
por: Zhu, Yueyao, et al.
Publicado: (2022)

Myosin VI and branched actin filaments mediate membrane constriction and fission of melanosomal tubule carriers
por: Ripoll, Léa, et al.
Publicado: (2018)

AP-1 and KIF13A coordinate endosomal sorting and positioning during melanosome biogenesis
por: Delevoye, Cédric, et al.
Publicado: (2009)

PI4P and BLOC-1 remodel endosomal membranes into tubules
por: Jani, Riddhi Atul, et al.
Publicado: (2022)

Mahogunin Ring Finger 1 regulates pigmentation by controlling the pH of melanosomes in melanocytes and melanoma cells
por: Sirés-Campos, Julia, et al.
Publicado: (2021)

Rab4A organizes endosomal domains for sorting cargo to lysosome-related organelles
por: Nag, Sudeshna, et al.
Publicado: (2018)

Distinct Protein Sorting and Localization to Premelanosomes, Melanosomes, and Lysosomes in Pigmented Melanocytic Cells(✪)
por: Raposo, Graça, et al.
Publicado: (2001)

AP-1/KIF13A Blocking Peptides Impair Melanosome Maturation and Melanin Synthesis
por: Campagne, Cécile, et al.
Publicado: (2018)

Proprotein convertase cleavage liberates a fibrillogenic fragment of a resident glycoprotein to initiate melanosome biogenesis
por: Berson, Joanne F., et al.
Publicado: (2003)

A role for Dynlt3 in melanosome movement, distribution, acidity and transfer
por: Aktary, Zackie, et al.
Publicado: (2021)

A BLOC-1–AP-3 super-complex sorts a cis-SNARE complex into endosome-derived tubular transport carriers
por: Bowman, Shanna L., et al.
Publicado: (2021)

Grd19/Snx3p functions as a cargo-specific adapter for retromer-dependent endocytic recycling
por: Strochlic, Todd I., et al.
Publicado: (2007)

NPC1 plays a role in the trafficking of specific cargo to melanosomes
por: Rus, Alina Adriana, et al.
Publicado: (2023)

Coming or going? Un-BLOC-ing delivery and recycling pathways during melanosome maturation
por: Futter, Clare E., et al.
Publicado: (2016)

KIF13A—A Key Regulator of Recycling Endosome Dynamics
por: Thankachan, Jerrin Mathew, et al.
Publicado: (2022)

Inactivation of Pmel Alters Melanosome Shape But Has Only a Subtle Effect on Visible Pigmentation
por: Hellström, Anders R., et al.
Publicado: (2011)

Epidermal Lamellar Body Biogenesis: Insight Into the Roles of Golgi and Lysosomes
por: Mahanty, Sarmistha, et al.
Publicado: (2021)

Correction for BLOC-1 Is Required for Cargo-specific Sorting from Vacuolar Early Endosomes toward Lysosome-related Organelles
Publicado: (2017)

Melanosomal Dynamics Assessed with a Live-Cell Fluorescent Melanosomal Marker
por: Bruder, Jan M., et al.
Publicado: (2012)

SNAREs in the maturation and function of LROs
por: Jani, Riddhi Atul, et al.
Publicado: (2016)

SLC45A2 protein stability and regulation of melanosome pH determine melanocyte pigmentation
por: Le, Linh, et al.
Publicado: (2020)

The size of the melanosome and photodamage of DNA.
por: Toda, K., et al.
Publicado: (1973)

THE FATE OF AMPHIBIAN EGG MELANOSOMES
por: Taylor, John D., et al.
Publicado: (1972)

It takes two to tango to the melanosome
por: Lakkaraju, Aparna, et al.
Publicado: (2009)

PIKfyve regulates melanosome biogenesis
por: Liggins, Marc C., et al.
Publicado: (2018)

Fossilization of melanosomes via sulfurization
por: McNamara, Maria E., et al.
Publicado: (2016)

Computational Investigation of the pH Dependence of Stability of Melanosome Proteins: Implication for Melanosome formation and Disease
por: Koirala, Mahesh, et al.
Publicado: (2021)

OCA7 is a melanosome membrane protein that defines pigmentation by regulating early stages of melanosome biogenesis
por: Beyers, Wyatt C., et al.
Publicado: (2022)

Rab1A regulates anterograde melanosome transport by recruiting kinesin-1 to melanosomes through interaction with SKIP
por: Ishida, Morié, et al.
Publicado: (2015)

Regulated Delivery of Molecular Cargo to Invasive Tumor-derived Microvesicles
por: Clancy, James W., et al.
Publicado: (2015)

To Bloc or Not to Bloc: Challenges in the Management of Patients Requesting “En-Bloc Capsulectomy”
por: Johal, Kavan S, et al.
Publicado: (2020)

On the shuttling across the blood-brain barrier via tubule formation: Mechanism and cargo avidity bias
por: Tian, Xiaohe, et al.
Publicado: (2020)

The ocular albinism type 1 protein, an intracellular G protein-coupled receptor, regulates melanosome transport in pigment cells
por: Palmisano, Ilaria, et al.
Publicado: (2008)

The ocular albinism type 1 protein, an intracellular G protein-coupled receptor, regulates melanosome transport in pigment cells
por: Palmisano, Ilaria, et al.
Publicado: (2017)

FERARI and cargo adaptors coordinate cargo flow through sorting endosomes
por: Solinger, Jachen A., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_iapblpvqlc8q3o5cdl6h034nfu