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Treatments for fibrosis of the corpora cavernosa
INTRODUCTION: Corporal fibrosis usually occurs after explantation of an infected penile prosthesis, severe penile trauma, refractory low-flow priapism, Peyronie’s disease, or the chronic intracavernous injection of vasoactive drugs. METHODS: We analysed current treatmentss for penile fibrosis. We se...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4443017/ https://www.ncbi.nlm.nih.gov/pubmed/26558095 http://dx.doi.org/10.1016/j.aju.2013.05.004 |
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author | Egydio, Paulo H. Kuehhas, Franklin E. |
author_facet | Egydio, Paulo H. Kuehhas, Franklin E. |
author_sort | Egydio, Paulo H. |
collection | PubMed |
description | INTRODUCTION: Corporal fibrosis usually occurs after explantation of an infected penile prosthesis, severe penile trauma, refractory low-flow priapism, Peyronie’s disease, or the chronic intracavernous injection of vasoactive drugs. METHODS: We analysed current treatmentss for penile fibrosis. We searched PubMed using the keywords ’penile corporal fibrosis’, ’treatment’ and ’penile fibrosis’, resulting in 63 matches, of which 19 articles met the inclusion criteria. RESULTS AND CONCLUSIONS: This review covers conservative medical therapy for corporal fibrosis and surgical therapeutic methods. The roles of phosphodiesterase- 5 inhibitors and pentoxifylline are analysed. Surgical therapy includes implantation of a penile prosthesis and corporal reconstruction, and these are reviewed. Corporal fibrosis is a major problem for patients, and is associated with severe erectile dysfunction. Conservative treatment options can be applicable in the early phase, but simultaneous corporal reconstruction procedures with concomitant implantation of a penile prosthesis should be attempted in severe cases of corporal fibrosis. |
format | Online Article Text |
id | pubmed-4443017 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-44430172015-11-10 Treatments for fibrosis of the corpora cavernosa Egydio, Paulo H. Kuehhas, Franklin E. Arab J Urol Review INTRODUCTION: Corporal fibrosis usually occurs after explantation of an infected penile prosthesis, severe penile trauma, refractory low-flow priapism, Peyronie’s disease, or the chronic intracavernous injection of vasoactive drugs. METHODS: We analysed current treatmentss for penile fibrosis. We searched PubMed using the keywords ’penile corporal fibrosis’, ’treatment’ and ’penile fibrosis’, resulting in 63 matches, of which 19 articles met the inclusion criteria. RESULTS AND CONCLUSIONS: This review covers conservative medical therapy for corporal fibrosis and surgical therapeutic methods. The roles of phosphodiesterase- 5 inhibitors and pentoxifylline are analysed. Surgical therapy includes implantation of a penile prosthesis and corporal reconstruction, and these are reviewed. Corporal fibrosis is a major problem for patients, and is associated with severe erectile dysfunction. Conservative treatment options can be applicable in the early phase, but simultaneous corporal reconstruction procedures with concomitant implantation of a penile prosthesis should be attempted in severe cases of corporal fibrosis. Elsevier 2013-09 2013-07-09 /pmc/articles/PMC4443017/ /pubmed/26558095 http://dx.doi.org/10.1016/j.aju.2013.05.004 Text en © 2013 Production and hosting by Elsevier B.V. on behalf of Arab Association of Urology. http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/3.0/). |
spellingShingle | Review Egydio, Paulo H. Kuehhas, Franklin E. Treatments for fibrosis of the corpora cavernosa |
title | Treatments for fibrosis of the corpora cavernosa |
title_full | Treatments for fibrosis of the corpora cavernosa |
title_fullStr | Treatments for fibrosis of the corpora cavernosa |
title_full_unstemmed | Treatments for fibrosis of the corpora cavernosa |
title_short | Treatments for fibrosis of the corpora cavernosa |
title_sort | treatments for fibrosis of the corpora cavernosa |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4443017/ https://www.ncbi.nlm.nih.gov/pubmed/26558095 http://dx.doi.org/10.1016/j.aju.2013.05.004 |
work_keys_str_mv | AT egydiopauloh treatmentsforfibrosisofthecorporacavernosa AT kuehhasfrankline treatmentsforfibrosisofthecorporacavernosa |