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The incidence of late prosthetic joint infections: A registry-based study of 112,708 primary hip and knee replacements
BACKGROUND AND PURPOSE: Late prosthetic joint infections (PJIs) are a growing medical challenge as more and more joint replacements are being performed and the expected lifespan of patients is increasing. We analyzed the incidence rate of late PJI and its temporal trends in a nationwide population....
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Informa Healthcare
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4443453/ https://www.ncbi.nlm.nih.gov/pubmed/25813645 http://dx.doi.org/10.3109/17453674.2015.1035173 |
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author | Huotari, Kaisa Peltola, Mikko Jämsen, Esa |
author_facet | Huotari, Kaisa Peltola, Mikko Jämsen, Esa |
author_sort | Huotari, Kaisa |
collection | PubMed |
description | BACKGROUND AND PURPOSE: Late prosthetic joint infections (PJIs) are a growing medical challenge as more and more joint replacements are being performed and the expected lifespan of patients is increasing. We analyzed the incidence rate of late PJI and its temporal trends in a nationwide population. PATIENTS AND METHODS: 112,708 primary hip and knee replacements performed due to primary osteoarthritis (OA) between 1998 and 2009 were followed for a median time of 5 (1–13) years, using data from nationwide Finnish health registries. Late PJI was detected > 2 years postoperatively, and very late PJI was detected > 5 years postoperatively. RESULTS: During the follow-up, involving 619,299 prosthesis-years, 1,345 PJIs were registered: cumulative incidence 1.20% (95% CI: 1.13–1.26) (for knees, 1.41%; for hips, 0.92%). The incidence rate of late PJI was 0.069% per prosthesis-year (CI: 0.061–0.078), and it was greater after knee replacement than after hip replacement (0.080% vs. 0.057%, p = 0.006). The incidence rate of very late PJI was 0.051% per prosthesis-year (CI: 0.042–0.063), 0.058% for knees and 0.044% for hips (p = 0.2). The incidence rate of late PJI varied between 0.041% and 0.107% during the years of observation without any temporal trend (incidence rate ratio (IRR) = 0.98, 95% CI: 0.93–1.03). Very late PJI increased from 0.026% in 2004 to 0.056% in 2010 (IRR = 1.11, 95% CI: 1.02–1.20). INTERPRETATION: In our nationwide study, the incidence rate of late PJI after hip or knee arthroplasty was approximately 0.07% per prosthesis-year. The incidence of very late PJI appeared to increase. |
format | Online Article Text |
id | pubmed-4443453 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Informa Healthcare |
record_format | MEDLINE/PubMed |
spelling | pubmed-44434532015-06-08 The incidence of late prosthetic joint infections: A registry-based study of 112,708 primary hip and knee replacements Huotari, Kaisa Peltola, Mikko Jämsen, Esa Acta Orthop Hip BACKGROUND AND PURPOSE: Late prosthetic joint infections (PJIs) are a growing medical challenge as more and more joint replacements are being performed and the expected lifespan of patients is increasing. We analyzed the incidence rate of late PJI and its temporal trends in a nationwide population. PATIENTS AND METHODS: 112,708 primary hip and knee replacements performed due to primary osteoarthritis (OA) between 1998 and 2009 were followed for a median time of 5 (1–13) years, using data from nationwide Finnish health registries. Late PJI was detected > 2 years postoperatively, and very late PJI was detected > 5 years postoperatively. RESULTS: During the follow-up, involving 619,299 prosthesis-years, 1,345 PJIs were registered: cumulative incidence 1.20% (95% CI: 1.13–1.26) (for knees, 1.41%; for hips, 0.92%). The incidence rate of late PJI was 0.069% per prosthesis-year (CI: 0.061–0.078), and it was greater after knee replacement than after hip replacement (0.080% vs. 0.057%, p = 0.006). The incidence rate of very late PJI was 0.051% per prosthesis-year (CI: 0.042–0.063), 0.058% for knees and 0.044% for hips (p = 0.2). The incidence rate of late PJI varied between 0.041% and 0.107% during the years of observation without any temporal trend (incidence rate ratio (IRR) = 0.98, 95% CI: 0.93–1.03). Very late PJI increased from 0.026% in 2004 to 0.056% in 2010 (IRR = 1.11, 95% CI: 1.02–1.20). INTERPRETATION: In our nationwide study, the incidence rate of late PJI after hip or knee arthroplasty was approximately 0.07% per prosthesis-year. The incidence of very late PJI appeared to increase. Informa Healthcare 2015-06 2015-05-13 /pmc/articles/PMC4443453/ /pubmed/25813645 http://dx.doi.org/10.3109/17453674.2015.1035173 Text en Copyright: © Nordic Orthopaedic Federation http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open-access article distributed under the terms of the CC-BY-NC-ND 3.0 License which permits users to download and share the article for non-commercial purposes, so long as the article is reproduced in the whole without changes, and provided the original source is credited. |
spellingShingle | Hip Huotari, Kaisa Peltola, Mikko Jämsen, Esa The incidence of late prosthetic joint infections: A registry-based study of 112,708 primary hip and knee replacements |
title | The incidence of late prosthetic joint infections: A registry-based study of 112,708 primary hip and knee replacements |
title_full | The incidence of late prosthetic joint infections: A registry-based study of 112,708 primary hip and knee replacements |
title_fullStr | The incidence of late prosthetic joint infections: A registry-based study of 112,708 primary hip and knee replacements |
title_full_unstemmed | The incidence of late prosthetic joint infections: A registry-based study of 112,708 primary hip and knee replacements |
title_short | The incidence of late prosthetic joint infections: A registry-based study of 112,708 primary hip and knee replacements |
title_sort | incidence of late prosthetic joint infections: a registry-based study of 112,708 primary hip and knee replacements |
topic | Hip |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4443453/ https://www.ncbi.nlm.nih.gov/pubmed/25813645 http://dx.doi.org/10.3109/17453674.2015.1035173 |
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