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Structure and biosynthesis of a macrocyclic peptide containing an unprecedented lysine-to-tryptophan crosslink

Streptococcal bacteria use peptide signals as a means of intraspecies communication. These peptides can contain unusual post-translational modifications providing opportunities for expanding our understanding of Nature's chemical and biosynthetic repertoires. Herein we have combined tools from...

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Detalles Bibliográficos
Autores principales: Schramma, Kelsey R., Bushin, Leah B., Seyedsayamdost, Mohammad R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4443489/
https://www.ncbi.nlm.nih.gov/pubmed/25901822
http://dx.doi.org/10.1038/nchem.2237