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Intradiscal application of rhBMP-7 does not induce regeneration in a canine model of spontaneous intervertebral disc degeneration

INTRODUCTION: Strategies for biological repair and regeneration of the intervertebral disc (IVD) by cell and tissue engineering are promising, but few have made it into a clinical setting. Recombinant human bone morphogenetic protein 7 (rhBMP-7) has been shown to stimulate matrix production by IVD c...

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Detalles Bibliográficos
Autores principales:	Willems, Nicole, Bach, Frances C, Plomp, Saskia G M, van Rijen, Mattie HP, Wolfswinkel, Jeannette, Grinwis, Guy CM, Bos, Clemens, Strijkers, Gustav J, Dhert, Wouter JA, Meij, Björn P, Creemers, Laura B, Tryfonidou, Marianna A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4443547/ https://www.ncbi.nlm.nih.gov/pubmed/26013758 http://dx.doi.org/10.1186/s13075-015-0625-2

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