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Tobacco smoking is associated with methylation of genes related to coronary artery disease

BACKGROUND: Tobacco smoking, a risk factor for coronary artery disease (CAD), is known to modify DNA methylation. We hypothesized that tobacco smoking modifies methylation of the genes identified for CAD by genome-wide association study (GWAS). RESULTS: We selected genomic regions based on 150 singl...

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Detalles Bibliográficos
Autores principales:	Steenaard, Rebecca V, Ligthart, Symen, Stolk, Lisette, Peters, Marjolein J, van Meurs, Joyce B, Uitterlinden, Andre G, Hofman, Albert, Franco, Oscar H, Dehghan, Abbas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4443552/ https://www.ncbi.nlm.nih.gov/pubmed/26015811 http://dx.doi.org/10.1186/s13148-015-0088-y

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