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Keratoconus in vitro and the key players of the TGF-β pathway

Purpose: Keratoconus (KC) is a corneal thinning disease of unknown etiology whose pathophysiology is correlated with the presence of a thin corneal stroma and altered extracellular matrix (ECM). Transforming growth factor-β (TGF-β) signaling is a key regulator of ECM secretion and assembly in multip...

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Detalles Bibliográficos
Autores principales: Priyadarsini, Shrestha, McKay, Tina B., Sarker-Nag, Akhee, Karamichos, Dimitrios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2015
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4443584/
https://www.ncbi.nlm.nih.gov/pubmed/26015770