Cargando…

Epigenetic mechanisms of endothelial dysfunction in type 2 diabetes

The development of type-2 diabetes mellitus (T2DM) and its complications is largely due to the complex interaction between genetic factors and environmental influences, mainly dietary habits and lifestyle, which can either accelerate or slow down disease progression. Recent findings suggest the pote...

Descripción completa

Detalles Bibliográficos
Autores principales:	Prattichizzo, Francesco, Giuliani, Angelica, Ceka, Artan, Rippo, Maria Rita, Bonfigli, Anna Rita, Testa, Roberto, Procopio, Antonio Domenico, Olivieri, Fabiola
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4443613/ https://www.ncbi.nlm.nih.gov/pubmed/26015812 http://dx.doi.org/10.1186/s13148-015-0090-4

Ejemplares similares

Where Metabolism Meets Senescence: Focus on Endothelial Cells
por: Sabbatinelli, Jacopo, et al.
Publicado: (2019)

Prognostic value of soluble ST2, high-sensitivity cardiac troponin, and NT-proBNP in type 2 diabetes: a 15-year retrospective study
por: Sabbatinelli, Jacopo, et al.
Publicado: (2022)

The mitomiR/Bcl-2 axis affects mitochondrial function and autophagic vacuole formation in senescent endothelial cells
por: Giuliani, Angelica, et al.
Publicado: (2018)

Short-term sustained hyperglycaemia fosters an archetypal senescence-associated secretory phenotype in endothelial cells and macrophages
por: Prattichizzo, Francesco, et al.
Publicado: (2017)

Mitochondrial (Dys) Function in Inflammaging: Do MitomiRs Influence the Energetic, Oxidative, and Inflammatory Status of Senescent Cells?
por: Giuliani, Angelica, et al.
Publicado: (2017)

Corrigendum to “Mitochondrial (Dys) Function in Inflammaging: Do MitomiRs Influence the Energetic, Oxidative, and Inflammatory Status of Senescent Cells?”
por: Giuliani, Angelica, et al.
Publicado: (2019)

Toll like receptor signaling in “inflammaging”: microRNA as new players
por: Olivieri, Fabiola, et al.
Publicado: (2013)

Anti-TNF-α treatment modulates SASP and SASP-related microRNAs in endothelial cells and in circulating angiogenic cells
por: Prattichizzo, Francesco, et al.
Publicado: (2016)

MiR-21-5p and miR-126a-3p levels in plasma and circulating angiogenic cells: relationship with type 2 diabetes complications
por: Olivieri, Fabiola, et al.
Publicado: (2015)

Age- and glycemia-related miR-126-3p levels in plasma and endothelial cells
por: Olivieri, Fabiola, et al.
Publicado: (2014)

Leukocyte telomere length and mortality risk in patients with type 2 diabetes
por: Bonfigli, Anna Rita, et al.
Publicado: (2016)

Circulating biomarkers of inflammaging as potential predictors of COVID-19 severe outcomes
por: Sabbatinelli, Jacopo, et al.
Publicado: (2022)

Genome-Wide Methylation Changes Associated with Replicative Senescence and Differentiation in Endothelial and Bone Marrow Mesenchymal Stromal Cells
por: Giuliani, Angelica, et al.
Publicado: (2023)

Extracellular microRNAs and endothelial hyperglycaemic memory: a therapeutic opportunity?
por: Prattichizzo, F., et al.
Publicado: (2016)

DNA damage response (DDR) and senescence: shuttled inflamma-miRNAs on the stage of inflamm-aging
por: Olivieri, Fabiola, et al.
Publicado: (2015)

Long-term exposure of human endothelial cells to metformin modulates miRNAs and isomiRs
por: Giuliani, Angelica, et al.
Publicado: (2020)

Diagnostic value of microRNAs in asbestos exposure and malignant mesothelioma: systematic review and qualitative meta-analysis
por: Micolucci, Luigina, et al.
Publicado: (2016)

MicroRNAs as Factors in Bidirectional Crosstalk Between Mitochondria and the Nucleus During Cellular Senescence
por: Giordani, Chiara, et al.
Publicado: (2021)

The Experimental Pathology at Ancona: 50 Years of Exciting and Pioneering Research on Human Pathology
por: Olivieri, Fabiola, et al.
Publicado: (2020)

Ubiquinol Ameliorates Endothelial Dysfunction in Subjects with Mild-to-Moderate Dyslipidemia: A Randomized Clinical Trial
por: Sabbatinelli, Jacopo, et al.
Publicado: (2020)

Age-related modulation of plasmatic beta-Galactosidase activity in healthy subjects and in patients affected by T2DM
por: Spazzafumo, Liana, et al.
Publicado: (2017)

Sensitivity and specificity of in vivo COVID-19 screening by detection dogs: Results of the C19-Screendog multicenter study
por: Soggiu, Francesca, et al.
Publicado: (2023)

The “Metabolic Memory” Theory and the Early Treatment of Hyperglycemia in Prevention of Diabetic Complications
por: Testa, Roberto, et al.
Publicado: (2017)

Anti-Inflammatory Effects of Olive Leaf Extract and Its Bioactive Compounds Oleacin and Oleuropein-Aglycone on Senescent Endothelial and Small Airway Epithelial Cells
por: Silvestrini, Andrea, et al.
Publicado: (2023)

“Inflammaging” as a Druggable Target: A Senescence-Associated Secretory Phenotype—Centered View of Type 2 Diabetes
por: Prattichizzo, Francesco, et al.
Publicado: (2016)

Anti-inflammatory effect of SGLT-2 inhibitors via uric acid and insulin
por: La Grotta, Rosalba, et al.
Publicado: (2022)

MiR-422a promotes adipogenesis via MeCP2 downregulation in human bone marrow mesenchymal stem cells
por: Giuliani, Angelica, et al.
Publicado: (2023)

Small extracellular vesicles deliver miR-21 and miR-217 as pro-senescence effectors to endothelial cells
por: Mensà, Emanuela, et al.
Publicado: (2020)

Anti-SASP and anti-inflammatory activity of resveratrol, curcumin and β-caryophyllene association on human endothelial and monocytic cells
por: Matacchione, Giulia, et al.
Publicado: (2021)

Expression Levels and Clinical Significance of miR-21-5p, miR-let-7a, and miR-34c-5p in Laryngeal Squamous Cell Carcinoma
por: Re, Massimo, et al.
Publicado: (2017)

Modulation of soluble receptor for advanced glycation end-products (RAGE) isoforms and their ligands in healthy aging
por: Scavello, Francesco, et al.
Publicado: (2019)

Circulating inflamma-miRs in aging and age-related diseases
por: Olivieri, Fabiola, et al.
Publicado: (2013)

From Oxidative Stress Damage to Pathways, Networks, and Autophagy via MicroRNAs
por: Engedal, Nikolai, et al.
Publicado: (2018)

Inflamm-aging: Why older men are the most susceptible to SARS-CoV-2 complicated outcomes
por: Bonafè, Massimiliano, et al.
Publicado: (2020)

Replicative Senescence-Associated LINE1 Methylation and LINE1-Alu Expression Levels in Human Endothelial Cells
por: Ramini, Deborah, et al.
Publicado: (2022)

The Genetic Variability of Members of the SLC38 Family of Amino Acid Transporters (SLC38A3, SLC38A7 and SLC38A9) Affects Susceptibility to Type 2 Diabetes and Vascular Complications
por: Crocco, Paolina, et al.
Publicado: (2022)

Senescent Endothelial Cells Sustain Their Senescence-Associated Secretory Phenotype (SASP) through Enhanced Fatty Acid Oxidation
por: Giuliani, Angelica, et al.
Publicado: (2023)

Extracellular vesicle-shuttled miRNAs: a critical appraisal of their potential as nano-diagnostics and nano-therapeutics in type 2 diabetes mellitus and its cardiovascular complications
por: Prattichizzo, Francesco, et al.
Publicado: (2021)

Response to: Letter to the Editor on “Bonafè M, Prattichizzo F, Giuliani A, Storci G, Sabbatinelli J, Olivieri F. Inflamm-aging: Why older men are the most susceptible to SARS-CoV-2 complicated outcomes. Cytokine Growth Factor Rev” by Eugenia Quiros-Roldan, Giorgio Biasiotto and Isabella Zanella
por: Prattichizzo, Francesco, et al.
Publicado: (2021)

The Possible Protective Role of Glucagon-Like Peptide 1 on Endothelium During the Meal and Evidence for an “Endothelial Resistance” to Glucagon-Like Peptide 1 in Diabetes
por: Ceriello, Antonio, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_be1lr5itkrh44bufdbcbpkmebh