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Aneuploidy and chromosomal instability in cancer: a jackpot to chaos
Genomic instability (GIN) is a hallmark of cancer cells that facilitates the acquisition of mutations conferring aggressive or drug-resistant phenotypes during cancer evolution. Chromosomal instability (CIN) is a form of GIN that involves frequent cytogenetic changes leading to changes in chromosome...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4443636/ https://www.ncbi.nlm.nih.gov/pubmed/26015801 http://dx.doi.org/10.1186/s13008-015-0009-7 |