Cargando…

Integrative modeling reveals the principles of multi-scale chromatin boundary formation in human nuclear organization

BACKGROUND: Interphase chromosomes adopt a hierarchical structure, and recent data have characterized their chromatin organization at very different scales, from sub-genic regions associated with DNA-binding proteins at the order of tens or hundreds of bases, through larger regions with active or re...

Descripción completa

Detalles Bibliográficos
Autores principales: Moore, Benjamin L, Aitken, Stuart, Semple, Colin A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4443654/
https://www.ncbi.nlm.nih.gov/pubmed/26013771
http://dx.doi.org/10.1186/s13059-015-0661-x