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Integrative modeling reveals the principles of multi-scale chromatin boundary formation in human nuclear organization
BACKGROUND: Interphase chromosomes adopt a hierarchical structure, and recent data have characterized their chromatin organization at very different scales, from sub-genic regions associated with DNA-binding proteins at the order of tens or hundreds of bases, through larger regions with active or re...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4443654/ https://www.ncbi.nlm.nih.gov/pubmed/26013771 http://dx.doi.org/10.1186/s13059-015-0661-x |