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Comparison of the effects of moderate and severe hypercapnic acidosis on ventilation-induced lung injury
BACKGROUND: We have proved that hypercapnic acidosis (a PaCO(2) of 80-100 mmHg) protects against ventilator-induced lung injury in rats. However, there remains uncertainty regarding the appropriate target PaCO(2) or if greater CO(2) “doses” (PaCO(2) > 100 mmHg) demonstrate this effect. We wished...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4443663/ https://www.ncbi.nlm.nih.gov/pubmed/25924944 http://dx.doi.org/10.1186/s12871-015-0050-8 |