The Novel Functions of High-Molecular-Mass Complexes Containing Insulin Receptor Substrates in Mediation and Modulation of Insulin-Like Activities: Emerging Concept of Diverse Functions by IRS-Associated Proteins

Insulin-like peptides, such as insulin-like growth factors (IGFs) and insulin, induce a variety of bioactivities, such as growth, differentiation, survival, increased anabolism, and decreased catabolism in many cell types and in vivo. In general, IGFs or insulin bind to IGF-I receptor (IGF-IR) or in...

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Detalles Bibliográficos
Autores principales: Hakuno, Fumihiko, Fukushima, Toshiaki, Yoneyama, Yosuke, Kamei, Hiroyasu, Ozoe, Atsufumi, Yoshihara, Hidehito, Yamanaka, Daisuke, Shibano, Takashi, Sone-Yonezawa, Meri, Yu, Bu-Chin, Chida, Kazuhiro, Takahashi, Shin-Ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4443775/
https://www.ncbi.nlm.nih.gov/pubmed/26074875
http://dx.doi.org/10.3389/fendo.2015.00073

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