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Sodium-Assisted Formation of Binding and Traverse Conformations of the Substrate in a Neurotransmitter Sodium Symporter Model

Therapeutics designed to increase synaptic neurotransmitter levels by inhibiting neurotransmitter sodium symporters (NSSs) classify a strategic approach to treat brain disorders such as depression or epilepsy, however, the critical elementary steps that couple downhill flux of sodium to uphill trans...

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Detalles Bibliográficos
Autores principales: Simon, Ágnes, Bencsura, Ákos, Héja, László, Magyar, Csaba, Kardos, Julianna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4443782/
https://www.ncbi.nlm.nih.gov/pubmed/25138914
http://dx.doi.org/10.2174/1570163811666140812110735

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