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Regulation of α5 and αV Integrin Expression by GDF-5 and BMP-7 in Chondrocyte Differentiation and Osteoarthritis

The Integrin β1 family is the major receptors of the Extracellular matrix (ECM), and the synthesis and degradation balance of ECM is seriously disrupted during Osteoarthritis (OA). In this scenario, integrins modify their pattern expression and regulate chondrocyte differen-tiation in the articular...

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Detalles Bibliográficos
Autores principales: Garciadiego-Cázares, David, Aguirre-Sánchez, Hilda I., Abarca-Buis, René F., Kouri, Juan B., Velasquillo, Cristina, Ibarra, Clemente
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4443976/
https://www.ncbi.nlm.nih.gov/pubmed/26010756
http://dx.doi.org/10.1371/journal.pone.0127166