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A Function for the hnRNP A1/A2 Proteins in Transcription Elongation
The hnRNP A1 and A2 proteins regulate processes such as alternative pre-mRNA splicing and mRNA stability. Here, we report that a reduction in the levels of hnRNP A1 and A2 by RNA interference or their cytoplasmic retention by osmotic stress drastically increases the transcription of a reporter gene....
Autores principales: | Lemieux, Bruno, Blanchette, Marco, Monette, Anne, Mouland, Andrew J., Wellinger, Raymund J., Chabot, Benoit |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4444011/ https://www.ncbi.nlm.nih.gov/pubmed/26011126 http://dx.doi.org/10.1371/journal.pone.0126654 |
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