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Cambinol, a Novel Inhibitor of Neutral Sphingomyelinase 2 Shows Neuroprotective Properties

Ceramide is a bioactive lipid that plays an important role in stress responses leading to apoptosis, cell growth arrest and differentiation. Ceramide production is due in part to sphingomyelin hydrolysis by sphingomyelinases. In brain, neutral sphingomyelinase 2 (nSMase2) is expressed in neurons and...

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Detalles Bibliográficos
Autores principales:	Figuera-Losada, Mariana, Stathis, Marigo, Dorskind, Joelle M., Thomas, Ajit G., Bandaru, Veera Venkata Ratnam, Yoo, Seung-Wan, Westwood, Nicholas J., Rogers, Graeme W., McArthur, Justin C., Haughey, Norman J., Slusher, Barbara S., Rojas, Camilo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4444023/ https://www.ncbi.nlm.nih.gov/pubmed/26010541 http://dx.doi.org/10.1371/journal.pone.0124481

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