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Enantioselective cis-β-lactam synthesis by intramolecular C–H functionalization from enoldiazoacetamides and derivative donor–acceptor cyclopropenes
β-Lactam derivatives are produced through intermediate donor–acceptor cyclopropene intermediates in high yield, exclusive cis-diastereoselectivity, and high enantiocontrol in a chiral dirhodium carboxylate catalyzed intramolecular C–H functionalization reaction of enoldiazoacetamides.
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Royal Society of Chemistry
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4444070/ https://www.ncbi.nlm.nih.gov/pubmed/26029355 http://dx.doi.org/10.1039/c4sc03991b |
| _version_ | 1782373076099399680 |
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| author | Xu, Xinfang Deng, Yongming Yim, David N. Zavalij, Peter Y. Doyle, Michael P. |
| author_facet | Xu, Xinfang Deng, Yongming Yim, David N. Zavalij, Peter Y. Doyle, Michael P. |
| author_sort | Xu, Xinfang |
| collection | PubMed |
| description | β-Lactam derivatives are produced through intermediate donor–acceptor cyclopropene intermediates in high yield, exclusive cis-diastereoselectivity, and high enantiocontrol in a chiral dirhodium carboxylate catalyzed intramolecular C–H functionalization reaction of enoldiazoacetamides. |
| format | Online Article Text |
| id | pubmed-4444070 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2015 |
| publisher | Royal Society of Chemistry |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-44440702016-04-01 Enantioselective cis-β-lactam synthesis by intramolecular C–H functionalization from enoldiazoacetamides and derivative donor–acceptor cyclopropenes Xu, Xinfang Deng, Yongming Yim, David N. Zavalij, Peter Y. Doyle, Michael P. Chem Sci Chemistry β-Lactam derivatives are produced through intermediate donor–acceptor cyclopropene intermediates in high yield, exclusive cis-diastereoselectivity, and high enantiocontrol in a chiral dirhodium carboxylate catalyzed intramolecular C–H functionalization reaction of enoldiazoacetamides. Royal Society of Chemistry 2015-04-01 2015-01-28 /pmc/articles/PMC4444070/ /pubmed/26029355 http://dx.doi.org/10.1039/c4sc03991b Text en This journal is © The Royal Society of Chemistry 2015 http://creativecommons.org/licenses/by/3.0/ This article is freely available. This article is licensed under a Creative Commons Attribution 3.0 Unported Licence (CC BY 3.0) |
| spellingShingle | Chemistry Xu, Xinfang Deng, Yongming Yim, David N. Zavalij, Peter Y. Doyle, Michael P. Enantioselective cis-β-lactam synthesis by intramolecular C–H functionalization from enoldiazoacetamides and derivative donor–acceptor cyclopropenes |
| title | Enantioselective cis-β-lactam synthesis by intramolecular C–H functionalization from enoldiazoacetamides and derivative donor–acceptor cyclopropenes
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| title_full | Enantioselective cis-β-lactam synthesis by intramolecular C–H functionalization from enoldiazoacetamides and derivative donor–acceptor cyclopropenes
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| title_fullStr | Enantioselective cis-β-lactam synthesis by intramolecular C–H functionalization from enoldiazoacetamides and derivative donor–acceptor cyclopropenes
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| title_full_unstemmed | Enantioselective cis-β-lactam synthesis by intramolecular C–H functionalization from enoldiazoacetamides and derivative donor–acceptor cyclopropenes
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| title_short | Enantioselective cis-β-lactam synthesis by intramolecular C–H functionalization from enoldiazoacetamides and derivative donor–acceptor cyclopropenes
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| title_sort | enantioselective cis-β-lactam synthesis by intramolecular c–h functionalization from enoldiazoacetamides and derivative donor–acceptor cyclopropenes |
| topic | Chemistry |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4444070/ https://www.ncbi.nlm.nih.gov/pubmed/26029355 http://dx.doi.org/10.1039/c4sc03991b |
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