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Drug-Metabolizing Activity, Protein and Gene Expression of UDP-Glucuronosyltransferases Are Significantly Altered in Hepatocellular Carcinoma Patients

UDP-glucuronosyltransferases (UGTs), the most important enzymes in body detoxification and homeostasis maintaining, govern the glucuronidation reaction of various endogenous and environmental carcinogens. The metabolic function of UGTs can be severely influenced by hepatocellular carcinoma (HCC), th...

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Detalles Bibliográficos
Autores principales: Lu, Linlin, Zhou, Juan, Shi, Jian, Peng, Xiao-juan, Qi, Xiao-xiao, Wang, Ying, Li, Fang-yuan, Zhou, Fu-Yuan, Liu, Liang, Liu, Zhong-Qiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4444081/
https://www.ncbi.nlm.nih.gov/pubmed/26010150
http://dx.doi.org/10.1371/journal.pone.0127524