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Drug-Metabolizing Activity, Protein and Gene Expression of UDP-Glucuronosyltransferases Are Significantly Altered in Hepatocellular Carcinoma Patients
UDP-glucuronosyltransferases (UGTs), the most important enzymes in body detoxification and homeostasis maintaining, govern the glucuronidation reaction of various endogenous and environmental carcinogens. The metabolic function of UGTs can be severely influenced by hepatocellular carcinoma (HCC), th...
Autores principales: | Lu, Linlin, Zhou, Juan, Shi, Jian, Peng, Xiao-juan, Qi, Xiao-xiao, Wang, Ying, Li, Fang-yuan, Zhou, Fu-Yuan, Liu, Liang, Liu, Zhong-Qiu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4444081/ https://www.ncbi.nlm.nih.gov/pubmed/26010150 http://dx.doi.org/10.1371/journal.pone.0127524 |
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