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Xanthohumol Inhibits Notch Signaling and Induces Apoptosis in Hepatocellular Carcinoma

Despite improvement in therapeutic strategies, median survival in advanced hepatocellular carcinoma (HCC) remains less than one year. Therefore, molecularly targeted compounds with less toxic profiles are needed. Xanthohumol (XN), a prenylated chalcone has been shown to have anti-proliferative effec...

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Detalles Bibliográficos
Autores principales:	Kunnimalaiyaan, Selvi, Sokolowski, Kevin M., Balamurugan, Mariappan, Gamblin, T. Clark, Kunnimalaiyaan, Muthusamy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4444108/ https://www.ncbi.nlm.nih.gov/pubmed/26011160 http://dx.doi.org/10.1371/journal.pone.0127464

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