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The Stapled AKAP Disruptor Peptide STAD-2 Displays Antimalarial Activity through a PKA-Independent Mechanism
Drug resistance poses a significant threat to ongoing malaria control efforts. Coupled with lack of a malaria vaccine, there is an urgent need for the development of new antimalarials with novel mechanisms of action and low susceptibility to parasite drug resistance. Protein Kinase A (PKA) has been...
Autores principales: | Flaherty, Briana R., Wang, Yuxiao, Trope, Edward C., Ho, Tienhuei G., Muralidharan, Vasant, Kennedy, Eileen J., Peterson, David S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4444124/ https://www.ncbi.nlm.nih.gov/pubmed/26010880 http://dx.doi.org/10.1371/journal.pone.0129239 |
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