Cargando…

The proportion of CD16(+)CD14(dim) monocytes increases with tumor cell load in bone marrow of patients with multiple myeloma

Multiple myeloma is an incurable cancer with expansion of malignant plasma cells in the bone marrow. Previous studies have shown that monocytes and macrophages in the bone marrow milieu are important for tumor growth and may play a role in the drug response. We therefore characterized monocytes in b...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sponaas, Anne M, Moen, Siv H, Liabakk, Nina B, Feyzi, Emadoldin, Holien, Toril, Kvam, Solveig, Grøseth, Lill Anny G, Størdal, Berit, Buene, Glenn, Espevik, Terje, Waage, Anders, Standal, Therese, Sundan, Anders
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BlackWell Publishing Ltd 2015
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4444152/ https://www.ncbi.nlm.nih.gov/pubmed/26029369 http://dx.doi.org/10.1002/iid3.53

Ejemplares similares

PDL1 Expression on Plasma and Dendritic Cells in Myeloma Bone Marrow Suggests Benefit of Targeted anti PD1-PDL1 Therapy
por: Sponaas, Anne-Marit, et al.
Publicado: (2015)

Bone Morphogenetic Protein 4 Gene Therapy in Mice Inhibits Myeloma Tumor Growth, But Has a Negative Impact on Bone
por: Westhrin, Marita, et al.
Publicado: (2019)

MYC amplifications in myeloma cell lines: correlation with MYC-inhibitor efficacy
por: Holien, Toril, et al.
Publicado: (2015)

Correction: MYC amplifications in myeloma cell lines: correlation with MYC-inhibitor efficacy
por: Holien, Toril, et al.
Publicado: (2018)

Caspase‐8 regulates the expression of pro‐ and anti‐inflammatory cytokines in human bone marrow‐derived mesenchymal stromal cells
por: Moen, Siv H., et al.
Publicado: (2016)

Hydroxychloroquine potentiates carfilzomib toxicity towards myeloma cells
por: Baranowska, Katarzyna, et al.
Publicado: (2016)

PD1 is expressed on exhausted T cells as well as virus specific memory CD8+ T cells in the bone marrow of myeloma patients
por: Sponaas, Anne-Marit, et al.
Publicado: (2018)

Oncogene addiction to c-MYC in myeloma cells
por: Holien, Toril, et al.
Publicado: (2012)

TGF-β contamination of purified recombinant GDF15
por: Olsen, Oddrun Elise, et al.
Publicado: (2017)

Conversion of ATP to adenosine by CD39 and CD73 in multiple myeloma can be successfully targeted together with adenosine receptor A2A blockade
por: Yang, Rui, et al.
Publicado: (2020)

Bystander Memory T Cells and IMiD/Checkpoint Therapy in Multiple Myeloma: A Dangerous Tango?
por: Sponaas, Anne Marit, et al.
Publicado: (2021)

Chemerin is elevated in multiple myeloma patients and is expressed by stromal cells and pre-adipocytes
por: Westhrin, Marita, et al.
Publicado: (2018)

Intracellular glutathione determines bortezomib cytotoxicity in multiple myeloma cells
por: Starheim, K K, et al.
Publicado: (2016)

Bone morphogenetic protein-9 suppresses growth of myeloma cells by signaling through ALK2 but is inhibited by endoglin
por: Olsen, O E, et al.
Publicado: (2014)

Intracellular IL-32 regulates mitochondrial metabolism, proliferation, and differentiation of malignant plasma cells
por: Aass, Kristin Roseth, et al.
Publicado: (2021)

Monitoring multiple myeloma by quantification of recurrent mutations in serum
por: Rustad, Even Holth, et al.
Publicado: (2017)

c-Met signaling promotes IL-6-induced myeloma cell proliferation
por: Hov, Håkon, et al.
Publicado: (2009)

Activin A inhibits BMP-signaling by binding ACVR2A and ACVR2B
por: Olsen, Oddrun Elise, et al.
Publicado: (2015)

CD56(dim)CD16(dim) Natural Killer (NK) Cells: The Forgotten Population
por: Zimmer, Jacques
Publicado: (2020)

Compartmentalization of TNF and IL-6 in meningitis and septic shock
por: Waage, Anders, et al.
Publicado: (1993)

Human CD56(dim)CD16(dim) Cells As an Individualized Natural Killer Cell Subset
por: Amand, Mathieu, et al.
Publicado: (2017)

Identification of the source of elevated hepatocyte growth factor levels in multiple myeloma patients
por: Rampa, Christoph, et al.
Publicado: (2014)

CD32 is enriched on CD4(dim)CD8(bright) T cells
por: Virdi, Amber K., et al.
Publicado: (2020)

Erythropoietin (EPO)-receptor signaling induces cell death of primary myeloma cells in vitro
por: Våtsveen, Thea Kristin, et al.
Publicado: (2016)

Increased early activation of CD56(dim)CD16(dim/-) natural killer cells in immunological non-responders correlates with CD4(+) T-cell recovery
por: Zhang, Qiu-Yue, et al.
Publicado: (2020)

Distinguishing Human Peripheral Blood NK Cells from CD56(dim)CD16(dim)CD69(+)CD103(+) Resident Nasal Mucosal Lavage Fluid Cells
por: Rebuli, Meghan E., et al.
Publicado: (2018)

Beryllium Increases the CD14(dim)CD16+ Subset in the Lung of Chronic Beryllium Disease
por: Li, Li, et al.
Publicado: (2015)

Detection and Significance of CD4+CD25+CD127dim Regulatory T Cells in Individuals with Severe Aplastic Anemia
por: Qi, Weiwei, et al.
Publicado: (2015)

Changes in the Monocytic Subsets CD14(dim)CD16(+) and CD14(++)CD16(−) in Chronic Systolic Heart Failure Patients
por: Amir, Offer, et al.
Publicado: (2012)

CD45(dim)CD34(+)CD38(−)CD133(+) cells have the potential as leukemic stem cells in acute myeloid leukemia
por: Heo, Sook-Kyoung, et al.
Publicado: (2020)

Targeting Proliferating Cell Nuclear Antigen and Its Protein Interactions Induces Apoptosis in Multiple Myeloma Cells
por: Müller, Rebekka, et al.
Publicado: (2013)

Distinct Signatures in the Receptor Repertoire Discriminate CD56bright and CD56dim Natural Killer Cells
por: Schwane, Vera, et al.
Publicado: (2020)

Integration of CD34(+)CD117(dim) population signature improves the prognosis prediction of acute myeloid leukemia
por: Li, Xue-Ping, et al.
Publicado: (2022)

Increases in inflammatory and CD14(dim)/CD16(pos)/CD45(pos) patrolling monocytes in sepsis: correlation with final outcome
por: Gainaru, Gabriela, et al.
Publicado: (2018)

ERK1/2, MEK1/2 and p38 downstream signalling molecules impaired in CD56(dim)CD16(+) and CD56(bright)CD16(dim/−) natural killer cells in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis patients
por: Huth, Teilah Kathryn, et al.
Publicado: (2016)

Evaluation of CD56(dim) and CD56(bright) natural killer cells in peripheral blood of women with IVF failures
por: Mardanian, Farahnaz, et al.
Publicado: (2015)

CD56(dim)CD16(high) and CD56(bright)CD16(−) cell percentages associated with maximum knee extensor strength and incidence of death in elderly
por: Senpuku, Hidenobu, et al.
Publicado: (2016)

Human Natural Killer Cell Maturation Defect Supports In Vivo CD56(bright) to CD56(dim) Lineage Development
por: Domaica, Carolina Inés, et al.
Publicado: (2012)

NK cells CD56(bright) and CD56(dim) subset cytokine loss and exhaustion is associated with impaired survival in myeloma
por: Seymour, Frances, et al.
Publicado: (2022)

Functional TRPA1 Channels Regulate CD56(dim)CD16(+) NK Cell Cytotoxicity against Tumor Cells
por: Scopelliti, Fernanda, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_mobcp95srm449r0bmbgc2gofgd