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Investigation of IRES Insertion into the Genome of Recombinant MVA as a Translation Enhancer in the Context of Transcript Decapping

Recombinant modified vaccinia virus Ankara (MVA) has been used to deliver vaccine candidate antigens against infectious diseases and cancer. MVA is a potent viral vector for inducing high magnitudes of antigen-specific CD8(+) T cells; however the cellular immune responses to a recombinant antigen in...

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Detalles Bibliográficos
Autores principales:	Alharbi, Naif Khalaf, Chinnakannan, Senthil K., Gilbert, Sarah C., Draper, Simon J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4444188/ https://www.ncbi.nlm.nih.gov/pubmed/26011541 http://dx.doi.org/10.1371/journal.pone.0127978

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