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Zearalenone Mycotoxin Affects Immune Mediators, MAPK Signalling Molecules, Nuclear Receptors and Genome-Wide Gene Expression in Pig Spleen

The toxicity of zearalenone (ZEA) was evaluated in swine spleen, a key organ for the innate and adaptative immune response. Weaned pigs were fed for 18 days with a control or a ZEA contaminated diet. The effect of ZEA was assessed on wide genome expression, pro- (TNF-α, IL-8, IL-6, IL-1β, IFN-γ) and...

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Detalles Bibliográficos
Autores principales: Pistol, Gina Cecilia, Braicu, Cornelia, Motiu, Monica, Gras, Mihail Alexandru, Marin, Daniela Eliza, Stancu, Mariana, Calin, Loredana, Israel-Roming, Florentina, Berindan-Neagoe, Ioana, Taranu, Ionelia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4444191/
https://www.ncbi.nlm.nih.gov/pubmed/26011631
http://dx.doi.org/10.1371/journal.pone.0127503