Selective Blockade of Interferon-α and -β Reveals Their Non-Redundant Functions in a Mouse Model of West Nile Virus Infection

Although type I interferons (IFNs) were first described almost 60 years ago, the ability to monitor and modulate the functional activities of the individual IFN subtypes that comprise this family has been hindered by a lack of reagents. The major type I IFNs, IFN-β and the multiple subtypes of IFN-α...

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Detalles Bibliográficos
Autores principales: Sheehan, Kathleen C. F., Lazear, Helen M., Diamond, Michael S., Schreiber, Robert D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4444312/
https://www.ncbi.nlm.nih.gov/pubmed/26010249
http://dx.doi.org/10.1371/journal.pone.0128636

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