Cardiac-Specific SOCS3 Deletion Prevents In Vivo Myocardial Ischemia Reperfusion Injury through Sustained Activation of Cardioprotective Signaling Molecules

Myocardial ischemia reperfusion injury (IRI) adversely affects cardiac performance and the prognosis of patients with acute myocardial infarction. Although myocardial signal transducer and activator of transcription (STAT) 3 is potently cardioprotective during IRI, the inhibitory mechanism responsib...

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Detalles Bibliográficos
Autores principales: Nagata, Takanobu, Yasukawa, Hideo, Kyogoku, Sachiko, Oba, Toyoharu, Takahashi, Jinya, Nohara, Shoichiro, Minami, Tomoko, Mawatari, Kazutoshi, Sugi, Yusuke, Shimozono, Koutatsu, Pradervand, Sylvain, Hoshijima, Masahiko, Aoki, Hiroki, Fukumoto, Yoshihiro, Imaizumi, Tsutomu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4444323/
https://www.ncbi.nlm.nih.gov/pubmed/26010537
http://dx.doi.org/10.1371/journal.pone.0127942

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