Kaurenoic Acid Possesses Leishmanicidal Activity by Triggering a NLRP12/IL-1β/cNOS/NO Pathway

Leishmania amazonensis (L. amazonensis) infection can cause severe local and diffuse injuries in humans, a condition clinically known as American cutaneous leishmaniasis (ACL). Currently, the therapeutic approach for ACL is based on Glucantime, which shows high toxicity and poor effectiveness. There...

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Detalles Bibliográficos
Autores principales: Miranda, Milena Menegazzo, Panis, Carolina, da Silva, Suelen Santos, Macri, Juliana Aparecida, Kawakami, Natalia Yoshie, Hayashida, Thiago Hideki, Madeira, Tiago Bervelieri, Acquaro, Vinicius Ricardo, Nixdorf, Suzana Lucy, Pizzatti, Luciana, Ambrósio, Sérgio Ricardo, Cecchini, Rubens, Arakawa, Nilton Syogo, Verri, Waldiceu Aparecido, Conchon Costa, Ivete, Pavanelli, Wander Rogério
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4444587/
https://www.ncbi.nlm.nih.gov/pubmed/26074677
http://dx.doi.org/10.1155/2015/392918

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