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Molecular dynamics and principal components of potassium binding with human telomeric intra-molecular G-quadruplex

Telomere assumes intra-molecular G-quadruplex that is a significant drug target for inhibiting telomerase maintenance of telomeres in cancer. Metal cations have been recognized as playing important roles in stabilizing G-quadruplex, but their binding processes to human telomeric G-quadruplex remain...

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Detalles Bibliográficos
Autores principales:	Wang, Zhiguo, Chen, Ruping, Hou, Ling, Li, Jianfeng, Liu, Jun-Ping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Higher Education Press 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4444812/ https://www.ncbi.nlm.nih.gov/pubmed/25894091 http://dx.doi.org/10.1007/s13238-015-0155-3

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