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Silencing p75(NTR) prevents proNGF-induced endothelial cell death and development of acellular capillaries in rat retina
Accumulation of the nerve growth factor precursor (proNGF) and its receptor p75(NTR) have been associated with several neurodegenerative diseases in both brain and retina. However, whether proNGF contributes to microvascular degeneration remain unexplored. This study seeks to investigate the mechani...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4445004/ https://www.ncbi.nlm.nih.gov/pubmed/26029724 http://dx.doi.org/10.1038/mtm.2015.13 |