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Silencing p75(NTR) prevents proNGF-induced endothelial cell death and development of acellular capillaries in rat retina

Accumulation of the nerve growth factor precursor (proNGF) and its receptor p75(NTR) have been associated with several neurodegenerative diseases in both brain and retina. However, whether proNGF contributes to microvascular degeneration remain unexplored. This study seeks to investigate the mechani...

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Detalles Bibliográficos
Autores principales:	Shanab, Ahmed Y, Mysona, Barbara A, Matragoon, Suraporn, El-Remessy, Azza B
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4445004/ https://www.ncbi.nlm.nih.gov/pubmed/26029724 http://dx.doi.org/10.1038/mtm.2015.13

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